Tetrahydrobiopterin availability directly regulates eNOS coupling in tet-regulatable cells

Geahča maid

• Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.
  Dahkki: Crabtree, M, et al.
  Almmustuhtton: (2009)
• Tetrahydrobiopterin- and glutathionylation-dependent regulation of eNOS coupling: Relationships revealed by eNOS glutathionylation mutants in cells with tet-regulated GTP cyclohydrolase I expression
  Dahkki: Crabtree, M, et al.
  Almmustuhtton: (2012)
• Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
  Dahkki: Bendall, J, et al.
  Almmustuhtton: (2005)
• Tetrahydrobiopterin-dependent eNOS coupling determines vascular remodeling through accelerated endothelial regeneration
  Dahkki: Ali, Z, et al.
  Almmustuhtton: (2007)
• Tetrahydrobiopterin-dependent eNOS coupling mediates endothelial regeneration and attenuates vein graft atherosclerosis in ApoE-KO mice
  Dahkki: Ali, Z, et al.
  Almmustuhtton: (2007)