A new family of cinchona-derived bifunctional asymmetric phase-transfer catalysts: application to the enantio- and diastereoselective nitro-Mannich reaction of amidosulfones.

A new family of bifunctional H-bond donor phase-transfer catalysts derived from cinchona alkaloids has been developed and evaluated in the enantio- and diastereoselective nitro-Mannich reaction of in situ generated N-Boc-protected imines of aliphatic, aromatic, and heteroaromatic aldehydes. Under op...

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Bibliographic Details
Main Authors: Johnson, K, Rattley, MS, Sladojevich, F, Barber, D, Nuñez, MG, Goldys, A, Dixon, D
Format: Journal article
Language:English
Published: 2012