Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes.
The action of repaglinide, a novel insulin secretagogue, was compared with the sulfonylurea glibenclamide with regard to the hypoglycemic action in vivo, binding to betaTC-3 cells, insulin secretion from perifused mouse islets, and capacity to stimulate exocytosis by direct interaction with the secr...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1998
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