Common and rare variants in multifactorial susceptibility to common diseases.
Here, we give a historical overview of the search for genetic variants that influence the susceptibility of an individual to a chronic disease, from RA Fisher's seminal work to the current excitement of whole-genome association studies (WGAS). We then discuss the concepts behind the identificat...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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