Common and rare variants in multifactorial susceptibility to common diseases.

Common and rare variants in multifactorial susceptibility to common diseases.

Here, we give a historical overview of the search for genetic variants that influence the susceptibility of an individual to a chronic disease, from RA Fisher's seminal work to the current excitement of whole-genome association studies (WGAS). We then discuss the concepts behind the identificat...

Полное описание

Библиографические подробности
Главные авторы:	Bodmer, W, Bonilla, C
Формат:	Journal article
Язык:	English
Опубликовано:	2008

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