Common and rare variants in multifactorial susceptibility to common diseases.

Here, we give a historical overview of the search for genetic variants that influence the susceptibility of an individual to a chronic disease, from RA Fisher's seminal work to the current excitement of whole-genome association studies (WGAS). We then discuss the concepts behind the identificat...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Bodmer, W, Bonilla, C
Format: Journal article
Sprog:English
Udgivet: 2008