Common and rare variants in multifactorial susceptibility to common diseases.

Here, we give a historical overview of the search for genetic variants that influence the susceptibility of an individual to a chronic disease, from RA Fisher's seminal work to the current excitement of whole-genome association studies (WGAS). We then discuss the concepts behind the identificat...

Повний опис

Бібліографічні деталі
Автори: Bodmer, W, Bonilla, C
Формат: Journal article
Мова:English
Опубліковано: 2008