Tumour-stromal interactions in acid-mediated invasion: a mathematical model.

It is well established that the tumour microenvironment can both promote and suppress tumour growth and invasion, however, most mathematical models of invasion view the normal tissue as inhibiting tumour progression via immune modulation or spatial constraint. In particular, the production of acid b...

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Bibliographic Details
Main Authors: Martin, N, Gaffney, E, Gatenby, R, Maini, P
Format: Journal article
Language:English
Published: 2010