Traceless rhodium-catalyzed hydroacylation using alkyl aldehydes: the enantioselective synthesis of β-aryl ketones

A one-pot three-step sequence involving Rh-catalyzed alkene hydroacylation, sulfide elimination and Rh-catalyzed aryl boronic acid conjugate addition, delivers products of traceless chelation-controlled hydroacylation employing alkyl aldehydes. The stereodefined β-aryl ketones are obtained in good y...

Full description

Bibliographic Details
Main Authors: Willis, M, Bouisseau, A, Gao, M
Format: Journal article
Published: Wiley 2016