Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum-infected erythrocytes
A major determinant of pathogenicity in malaria caused by Plasmodium falciparum is the adhesion of parasite-infected erythrocytes to the vasculature or tissues of infected individuals. This occludes blood flow, leads to inflammation, and increases parasitemia by reducing spleen-mediated clearance of...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
National Academy of Sciences
2019
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