Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum-infected erythrocytes
A major determinant of pathogenicity in malaria caused by Plasmodium falciparum is the adhesion of parasite-infected erythrocytes to the vasculature or tissues of infected individuals. This occludes blood flow, leads to inflammation, and increases parasitemia by reducing spleen-mediated clearance of...
Үндсэн зохиолчид: | Lennartz, F, Smith, C, Craig, A, Higgins, M |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
National Academy of Sciences
2019
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Ижил төстэй зүйлс
Ижил төстэй зүйлс
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In silico guided reconstruction and analysis of ICAM-1-binding var genes from 1 Plasmodium falciparum
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The binding site on ICAM-1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site.
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An analysis of ICAM-1 in Plasmodium falciparum malaria.
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Хэвлэсэн: (2008) -
Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding
-н: Lennartz, F, зэрэг
Хэвлэсэн: (2015)