Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum-infected erythrocytes

A major determinant of pathogenicity in malaria caused by Plasmodium falciparum is the adhesion of parasite-infected erythrocytes to the vasculature or tissues of infected individuals. This occludes blood flow, leads to inflammation, and increases parasitemia by reducing spleen-mediated clearance of...

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Những tác giả chính: Lennartz, F, Smith, C, Craig, A, Higgins, M
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: National Academy of Sciences 2019

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