STEREOSPECIFIC AMINO-ACID SYNTHESIS - PREPARATION OF THE GAMMA-ANION DERIVED FROM GLUTAMIC-ACID
Reaction of α-t-butyl γ-methyl N-trityl-L-glutamate (7) with lithium isopropylcyclohexylamide in hexane leads to the specific formation of the γ-ester enolate, a potential synthetic equivalent to the γ-anion synthon for stereospecific α-amino acid synthesis.
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
1988
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