STEREOSPECIFIC AMINO-ACID SYNTHESIS - PREPARATION OF THE GAMMA-ANION DERIVED FROM GLUTAMIC-ACID
Reaction of α-t-butyl γ-methyl N-trityl-L-glutamate (7) with lithium isopropylcyclohexylamide in hexane leads to the specific formation of the γ-ester enolate, a potential synthetic equivalent to the γ-anion synthon for stereospecific α-amino acid synthesis.
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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1988
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| _version_ | 1797094874204340224 |
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| author | Baldwin, J North, M Flinn, A Moloney, M |
| author_facet | Baldwin, J North, M Flinn, A Moloney, M |
| author_sort | Baldwin, J |
| collection | OXFORD |
| description | Reaction of α-t-butyl γ-methyl N-trityl-L-glutamate (7) with lithium isopropylcyclohexylamide in hexane leads to the specific formation of the γ-ester enolate, a potential synthetic equivalent to the γ-anion synthon for stereospecific α-amino acid synthesis. |
| first_indexed | 2024-03-07T04:20:00Z |
| format | Journal article |
| id | oxford-uuid:cab476de-41ba-4c53-87ec-32f8b38f0b66 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:20:00Z |
| publishDate | 1988 |
| record_format | dspace |
| spelling | oxford-uuid:cab476de-41ba-4c53-87ec-32f8b38f0b662022-03-27T07:09:19ZSTEREOSPECIFIC AMINO-ACID SYNTHESIS - PREPARATION OF THE GAMMA-ANION DERIVED FROM GLUTAMIC-ACIDJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:cab476de-41ba-4c53-87ec-32f8b38f0b66EnglishSymplectic Elements at Oxford1988Baldwin, JNorth, MFlinn, AMoloney, MReaction of α-t-butyl γ-methyl N-trityl-L-glutamate (7) with lithium isopropylcyclohexylamide in hexane leads to the specific formation of the γ-ester enolate, a potential synthetic equivalent to the γ-anion synthon for stereospecific α-amino acid synthesis. |
| spellingShingle | Baldwin, J North, M Flinn, A Moloney, M STEREOSPECIFIC AMINO-ACID SYNTHESIS - PREPARATION OF THE GAMMA-ANION DERIVED FROM GLUTAMIC-ACID |
| title | STEREOSPECIFIC AMINO-ACID SYNTHESIS - PREPARATION OF THE GAMMA-ANION DERIVED FROM GLUTAMIC-ACID |
| title_full | STEREOSPECIFIC AMINO-ACID SYNTHESIS - PREPARATION OF THE GAMMA-ANION DERIVED FROM GLUTAMIC-ACID |
| title_fullStr | STEREOSPECIFIC AMINO-ACID SYNTHESIS - PREPARATION OF THE GAMMA-ANION DERIVED FROM GLUTAMIC-ACID |
| title_full_unstemmed | STEREOSPECIFIC AMINO-ACID SYNTHESIS - PREPARATION OF THE GAMMA-ANION DERIVED FROM GLUTAMIC-ACID |
| title_short | STEREOSPECIFIC AMINO-ACID SYNTHESIS - PREPARATION OF THE GAMMA-ANION DERIVED FROM GLUTAMIC-ACID |
| title_sort | stereospecific amino acid synthesis preparation of the gamma anion derived from glutamic acid |
| work_keys_str_mv | AT baldwinj stereospecificaminoacidsynthesispreparationofthegammaanionderivedfromglutamicacid AT northm stereospecificaminoacidsynthesispreparationofthegammaanionderivedfromglutamicacid AT flinna stereospecificaminoacidsynthesispreparationofthegammaanionderivedfromglutamicacid AT moloneym stereospecificaminoacidsynthesispreparationofthegammaanionderivedfromglutamicacid |