Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis.

Tuberculosis, one of the leading causes of death worldwide, stimulates inflammatory responses with beneficial and pathologic consequences. The regulation and nature of an optimal inflammatory response to Mycobacterium tuberculosis remains poorly understood in humans. Insight into mechanisms of negat...

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Bibliographic Details
Main Authors: Shah, J, Vary, J, Chau, T, Bang, N, Yen, N, Farrar, J, Dunstan, S, Hawn, T
Format: Journal article
Language:English
Published: 2012