Identification and characterisation of suppressors of synthetic lethality resulting from loss of SETD2 and WEE1
<p>Our lab has recently identified a conserved synthetic lethality between loss of SETD2-dependent H3K36 trimethylation and inhibition of WEE1 kinase (Pfister et al., 2015). In order to explore the possible mechanisms of resistance to WEE1 inhibitor-treatment in H3K36me3-deficient cells, a yea...
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2017
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