Identification and characterisation of suppressors of synthetic lethality resulting from loss of SETD2 and WEE1
<p>Our lab has recently identified a conserved synthetic lethality between loss of SETD2-dependent H3K36 trimethylation and inhibition of WEE1 kinase (Pfister et al., 2015). In order to explore the possible mechanisms of resistance to WEE1 inhibitor-treatment in H3K36me3-deficient cells, a yea...
| 1. autor: | |
|---|---|
| Kolejni autorzy: | |
| Format: | Praca dyplomowa |
| Wydane: |
2017
|