Regulation of angiogenesis by hypoxia: role of the HIF system.

The regulation of angiogenesis by hypoxia is an important component of homeostatic mechanisms that link vascular oxygen supply to metabolic demand. Molecular characterization of angiogenic pathways, identification of hypoxia-inducible factor (HIF) as a key transcriptional regulator of these molecule...

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Bibliographic Details
Main Authors: Pugh, C, Ratcliffe, P
Format: Journal article
Language:English
Published: 2003