Structural studies of integrin activation

<p>Fundamental to cell adhesion and migration, integrins are large heterodimeric membrane proteins that link the extracellular matrix to the actin cytoskeleton. Uniquely, these adhesion receptors mediate inside-out signal transduction, whereby extracellular adhesion is activated from within th...

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Bibliographic Details
Main Authors: Anthis, N, Nicholas J. Anthis
Other Authors: Campbell, I
Format: Thesis
Language:English
Published: 2009
Subjects: