MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer.

BACKGROUND and AIMS: Hereditary nonpolyposis colorectal cancer (HNPCC) is caused by heterozygous germline sequence mutations of DNA mismatch repair genes, most frequently MLH1 or MSH2. A novel molecular mechanism for HNPCC has recently been suggested by the finding of individuals with soma-wide mono...

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Bibliographic Details
Main Authors:	Hitchins, M, Williams, R, Cheong, K, Halani, N, Lin, V, Packham, D, Ku, S, Buckle, A, Hawkins, N, Burn, J, Gallinger, S, Goldblatt, J, Kirk, J, Tomlinson, I, Scott, R, Spigelman, A, Suter, C, Martin, D, Suthers, G, Ward, R
Format:	Journal article
Language:	English
Published:	2005

MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer.

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