Immune correlates of early clearance of Mycobacterium tuberculosis among tuberculosis household contacts in Indonesia

Some individuals, even when heavily exposed to an infectious tuberculosis patient, do not develop a specific T-cell response as measured by interferon-gamma release assay (IGRA). This could be explained by an IFN-γ-independent adaptive immune response, or an effective innate host response clearing M...

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Main Authors: Setiabudiawan, TP, Apriani, L, Verrall, AJ, Utami, F, Schneider, M, Indrati, AR, Halim, PP, Kaplonek, P, Malca, H, Lee, JS, Moorlag, SJCFM, de Bree, LCJ, Mourits, VP, Joosten, LAB, Netea, MG, Alisjahbana, B, McNamara, RP, Alter, G, van Laarhoven, A, Ussher, JE, Sharples, K, Koeken, VACM, Hill, PC, van Crevel, R
Format: Journal article
Language:English
Published: Nature Research 2025