Defects in mitochondrial clearance predispose human monocytes to interleukin-1β hypersecretion
<p style="text-align:justify;"> Most hereditary periodic fever syndromes are mediated by deregulated IL-1β secretion. The generation of mature IL-1β requires two signals: one that induces synthesis of inflammasome components and substrates and a second that activates inflammasomes....
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
American Society for Biochemistry and Molecular Biology
2014
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