The kinetics and phenotype of the human B-cell response following immunization with a heptavalent pneumococcal-CRM conjugate vaccine.

Primary immunization of infants with protein-polysaccharide conjugate vaccines induces antipolysaccharide antibody and is highly effective in preventing invasive disease caused by encapsulated bacteria. However, recent experience from the UK indicates that this immunity is not sustained in the absen...

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Bibliographic Details
Main Authors: Clutterbuck, E, Salt, P, Oh, S, Marchant, A, Beverley, P, Pollard, A
Format: Journal article
Language:English
Published: 2006