Investigating the role of Leucine Rich Repeat Kinase 2 (LRRK2) in human induced pluripotent stem cell derived macrophages

<p>Mutations in <em>Leucine Rich Repeat Kinase 2</em> (LRRK2) are the most prevalent cause of familial PD. Genome Wide Association Studies (GWAS) have linked its variants with increased risk of developing sporadic PD, inflammatory bowel disease, and leprosy, diseases commonly assoc...

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Bibliographic Details
Main Author: Lee, H
Other Authors: Cowley, S
Format: Thesis
Published: 2017