Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice.

Here we present a strategy to determine the genetic basis of variance in complex phenotypes that arise from natural, as opposed to induced, genetic variation in mice. We show that a commercially available strain of outbred mice, MF1, can be treated as an ultrafine mosaic of standard inbred strains a...

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Bibliographic Details
Main Authors: Yalcin, B, Willis-Owen, SA, Fullerton, J, Meesaq, A, Deacon, R, Rawlins, J, Copley, R, Morris, A, Flint, J, Mott, R
Format: Journal article
Language:English
Published: 2004