Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice.
Here we present a strategy to determine the genetic basis of variance in complex phenotypes that arise from natural, as opposed to induced, genetic variation in mice. We show that a commercially available strain of outbred mice, MF1, can be treated as an ultrafine mosaic of standard inbred strains a...
主要な著者: | Yalcin, B, Willis-Owen, SA, Fullerton, J, Meesaq, A, Deacon, R, Rawlins, J, Copley, R, Morris, A, Flint, J, Mott, R |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
2004
|
類似資料
-
Human-mouse quantitative trait locus concordance and the dissection of a human neuroticism locus.
著者:: Fullerton, J, 等
出版事項: (2008) -
Finding quantitative trait genes that influence mouse behaviour - and investigating their role in human psychopathology
著者:: Willis-Owen, S, 等
出版事項: (2005) -
Dissecting quantitative traits in mice.
著者:: Mott, R, 等
出版事項: (2013) -
Rgs 2 gene polymorphisms as modulators of anxiety in humans?
著者:: Leygraf, A, 等
出版事項: (2006) -
Investigation of RGS2 and RGS13 gene polymorphisms in human panic disorder
著者:: Hohoff, C, 等
出版事項: (2005)