Deracemisation of alpha-amino acids - (R)- and (S)-phenylalanine from the same enantiomer of a homochiral auxiliary

Chiral auxiliary (3S)-N,N'-bis-(p-methoxybenzyl)-3-isopropylpiperazine- 2,5-dione 1 was employed for the synthesis of both enantiomers of phenylalanine using a regioselective deprotonation/stereoselective reprotonation strategy. Modification of this approach enables the efficient deracemisation...

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Bibliographic Details
Main Authors: Bull, S, Davies, S, Epstein, S, Ouzman, J
Format: Journal article
Language:English
Published: 1998