Deracemisation of alpha-amino acids - (R)- and (S)-phenylalanine from the same enantiomer of a homochiral auxiliary
Chiral auxiliary (3S)-N,N'-bis-(p-methoxybenzyl)-3-isopropylpiperazine- 2,5-dione 1 was employed for the synthesis of both enantiomers of phenylalanine using a regioselective deprotonation/stereoselective reprotonation strategy. Modification of this approach enables the efficient deracemisation...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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1998
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| _version_ | 1797094974318182400 |
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| author | Bull, S Davies, S Epstein, S Ouzman, J |
| author_facet | Bull, S Davies, S Epstein, S Ouzman, J |
| author_sort | Bull, S |
| collection | OXFORD |
| description | Chiral auxiliary (3S)-N,N'-bis-(p-methoxybenzyl)-3-isopropylpiperazine- 2,5-dione 1 was employed for the synthesis of both enantiomers of phenylalanine using a regioselective deprotonation/stereoselective reprotonation strategy. Modification of this approach enables the efficient deracemisation of (±)-phenylalanine. |
| first_indexed | 2024-03-07T04:21:22Z |
| format | Journal article |
| id | oxford-uuid:cb20db05-9c44-46ad-81fc-6a7d534d73cd |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:21:22Z |
| publishDate | 1998 |
| record_format | dspace |
| spelling | oxford-uuid:cb20db05-9c44-46ad-81fc-6a7d534d73cd2022-03-27T07:12:35ZDeracemisation of alpha-amino acids - (R)- and (S)-phenylalanine from the same enantiomer of a homochiral auxiliaryJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:cb20db05-9c44-46ad-81fc-6a7d534d73cdEnglishSymplectic Elements at Oxford1998Bull, SDavies, SEpstein, SOuzman, JChiral auxiliary (3S)-N,N'-bis-(p-methoxybenzyl)-3-isopropylpiperazine- 2,5-dione 1 was employed for the synthesis of both enantiomers of phenylalanine using a regioselective deprotonation/stereoselective reprotonation strategy. Modification of this approach enables the efficient deracemisation of (±)-phenylalanine. |
| spellingShingle | Bull, S Davies, S Epstein, S Ouzman, J Deracemisation of alpha-amino acids - (R)- and (S)-phenylalanine from the same enantiomer of a homochiral auxiliary |
| title | Deracemisation of alpha-amino acids - (R)- and (S)-phenylalanine from the same enantiomer of a homochiral auxiliary |
| title_full | Deracemisation of alpha-amino acids - (R)- and (S)-phenylalanine from the same enantiomer of a homochiral auxiliary |
| title_fullStr | Deracemisation of alpha-amino acids - (R)- and (S)-phenylalanine from the same enantiomer of a homochiral auxiliary |
| title_full_unstemmed | Deracemisation of alpha-amino acids - (R)- and (S)-phenylalanine from the same enantiomer of a homochiral auxiliary |
| title_short | Deracemisation of alpha-amino acids - (R)- and (S)-phenylalanine from the same enantiomer of a homochiral auxiliary |
| title_sort | deracemisation of alpha amino acids r and s phenylalanine from the same enantiomer of a homochiral auxiliary |
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