Structure of the CRISPR interference complex CSM reveals key similarities with cascade.

The Clustered Regularly Interspaced Palindromic Repeats (CRISPR) system is an adaptive immune system in prokaryotes. Interference complexes encoded by CRISPR-associated (cas) genes utilize small RNAs for homology-directed detection and subsequent degradation of invading genetic elements, and they ha...

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Bibliographic Details
Main Authors: Rouillon, C, Zhou, M, Zhang, J, Politis, A, Beilsten-Edmands, V, Cannone, G, Graham, S, Robinson, C, Spagnolo, L, White, M
Format: Journal article
Language:English
Published: 2013