Mechanistic insight into palladium-catalyzed cycloisomerization: a combined experimental and theoretical study

The cycloisomerization of enynes catalyzed by Pd(OAc)2 and bis-benzylidene ethylenediamine (bbeda) is a landmark methodology in transition-metal-catalyzed cycloisomerization. However, the mechanistic pathway by which this reaction proceeds has remained unclear for several decades. Here we describe m...

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Bibliographic Details
Main Authors: Mekareeya, A, Walker, P, Couce-Rios, A, Campbell, C, Steven, A, Paton, R, Anderson, E
Format: Journal article
Language:English
Published: American Chemical Society 2017