Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53).

AIMS: The beta-cell ATP-sensitive potassium channel consists of two subunits, SUR1 and Kir6.2. Population association studies have shown that three variants in SUR1 and one in Kir6.2 are associated with Type 2 diabetes. These polymorphisms do not result in a functional change or affect splicing, su...

詳細記述

書誌詳細
主要な著者: Gloyn, A, Hashim, Y, Ashcroft, S, Ashfield, R, Wiltshire, S, Turner, R
フォーマット: Journal article
言語:English
出版事項: 2001