Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?

Glutamatergic dysfunction is strongly implicated in schizophrenia and mood disorders. GluA1 knockout (KO) mice display schizophrenia- and depression-related abnormalities. Here, we asked whether GluA1 KO show mania-related abnormalities. KO were tested for behavior in approach/avoid conflict tests,...

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Bibliographic Details
Main Authors: Fitzgerald, P, Barkus, C, Feyder, M, Wiedholz, L, Chen, Y, Karlsson, R, Machado-Vieira, R, Graybeal, C, Sharp, T, Zarate, C, Harvey-White, J, Du, J, Sprengel, R, Gass, P, Bannerman, D, Holmes, A
Format: Journal article
Language:English
Published: 2010