Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?
Glutamatergic dysfunction is strongly implicated in schizophrenia and mood disorders. GluA1 knockout (KO) mice display schizophrenia- and depression-related abnormalities. Here, we asked whether GluA1 KO show mania-related abnormalities. KO were tested for behavior in approach/avoid conflict tests,...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2010
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