Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?
Glutamatergic dysfunction is strongly implicated in schizophrenia and mood disorders. GluA1 knockout (KO) mice display schizophrenia- and depression-related abnormalities. Here, we asked whether GluA1 KO show mania-related abnormalities. KO were tested for behavior in approach/avoid conflict tests,...
Հիմնական հեղինակներ: | Fitzgerald, P, Barkus, C, Feyder, M, Wiedholz, L, Chen, Y, Karlsson, R, Machado-Vieira, R, Graybeal, C, Sharp, T, Zarate, C, Harvey-White, J, Du, J, Sprengel, R, Gass, P, Bannerman, D, Holmes, A |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2010
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Նմանատիպ նյութեր
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Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?
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Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?
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Deletion of the GluA1 AMPA receptor subunit alters the expression of short-term memory.
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Impaired associative fear learning in mice with complete loss or haploinsufficiency of AMPA GluR1 receptors
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Հրապարակվել է: (2007-12-01)