Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?

Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?

Glutamatergic dysfunction is strongly implicated in schizophrenia and mood disorders. GluA1 knockout (KO) mice display schizophrenia- and depression-related abnormalities. Here, we asked whether GluA1 KO show mania-related abnormalities. KO were tested for behavior in approach/avoid conflict tests,...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Fitzgerald, P, Barkus, C, Feyder, M, Wiedholz, L, Chen, Y, Karlsson, R, Machado-Vieira, R, Graybeal, C, Sharp, T, Zarate, C, Harvey-White, J, Du, J, Sprengel, R, Gass, P, Bannerman, D, Holmes, A
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2010

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