19F‐NMR monitoring of reversible protein post‐translational modifications: class D β‐lactamase carbamylation and inhibition
Bacterial production of β‐lactamases with carbapenemase activity is a global health threat. The active sites of class D carbapenemases such as OXA‐48, which is of major clinical importance, uniquely contain a carbamylated lysine residue which is essential for catalysis. Although there is significant...
Հիմնական հեղինակներ: | , , , , , |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
Wiley
2019
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