Comparison of verona integron-borne metallo-β-lactamase (VIM) variants reveals differences in stability and inhibition profiles

<p style="text-align:justify;">Metallo-β-lactamases (MBLs) are of increasing clinical significance; the development of clinically useful MBL inhibitors is challenged by the rapid evolution of variant MBLs. The Verona integron-borne metallo-β-lactamase (VIM) enzymes are among the mos...

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Bibliographic Details
Main Authors: Makena, A, Duzgun, A, Brem, J, McDonough, M, Rydzik, A, Abboud, M, Saral, A, Cicek, A, Sandalli, C, Schofield, C
Format: Journal article
Language:English
Published: American Society for Microbiology 2016