Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state

<p><strong>Aims:&nbsp;</strong>CD40 and its ligand, CD40L, play a critical role in driving atherosclerotic plaque development. Disrupted CD40-signalling reduces experimental atherosclerosis and induces a favourable stable plaque phenotype. We recently showed that small molecule...

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Bibliographic Details
Main Authors: Bosmans, LA, van Tiel, CM, Aarts, SABM, Willemsen, L, Baardman, J, van Os, BW, den Toom, M, Beckers, L, Ahern, DJ, Levels, JHM, Jongejan, A, Moerland, PD, Verberk, SGS, van den Bossche, J, de Winther, MMPJ, Weber, C, Atzler, D, Monaco, C, Gerdes, N, Shami, A, Lutgens, E
Format: Journal article
Language:English
Published: Oxford University Press 2022