Pro-maturational effects of human iPSC-derived cortical astrocytes upon iPSC-derived cortical neurons

Astrocytes influence neuronal maturation and function by providing trophic support, regulating the extracellular environment, and modulating signaling at synapses. The emergence of induced pluripotent stem cell (iPSC) technology offers a human system with which to validate and re-evaluate insights f...

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Bibliographic Details
Main Authors: Anne Hedegaard, Jimena Monzón-Sandoval, Sarah E Newey, Emma S Whiteley, Caleb Webber, Colin J Akerman
Format: Journal article
Language:English
Published: Cell Press 2020