Structure and function of human 17beta-hydroxysteroid dehydrogenases.

17Beta-hydroxysteroid dehydrogenases (17beta-HSDs) catalyze the NAD(P)(H) dependent oxidoreduction at C17 oxo/beta-hydroxyl groups of androgen and estrogen hormones. This reversible reaction constitutes an important pre-receptor control mechanism for nuclear receptor ligands, since the conversion &q...

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Bibliographic Details
Main Authors: Lukacik, P, Kavanagh, K, Oppermann, U
Format: Journal article
Language:English
Published: 2006