Structure and function of human 17beta-hydroxysteroid dehydrogenases.
17Beta-hydroxysteroid dehydrogenases (17beta-HSDs) catalyze the NAD(P)(H) dependent oxidoreduction at C17 oxo/beta-hydroxyl groups of androgen and estrogen hormones. This reversible reaction constitutes an important pre-receptor control mechanism for nuclear receptor ligands, since the conversion &q...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2006
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