Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides
The lasso peptide microcin J25 is known to hijack the siderophore receptor FhuA for initiating internalization. Here, we provide what is to our knowledge the first structural evidence on the recognition mechanism, and our biochemical data show that another closely related lasso peptide cannot intera...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
Nature Publishing Group
2014
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