Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides

The lasso peptide microcin J25 is known to hijack the siderophore receptor FhuA for initiating internalization. Here, we provide what is to our knowledge the first structural evidence on the recognition mechanism, and our biochemical data show that another closely related lasso peptide cannot intera...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Mathavan, I, Zirah, S, Mehmood, S, Choudhury, H, Goulard, C, Li, Y, Robinson, C, Rebuffat, S, Beis, K
Format: Journal article
Sprog:English
Udgivet: Nature Publishing Group 2014