Male 11β-HSD1 knockout mice fed trans-fats and fructose are not protected from metabolic syndrome or nonalcoholic fatty liver disease.

Non-alcoholic fatty liver disease (NAFLD) defines a spectrum of diseases from simple steatosis to non-alcoholic steatohepatitis (NASH) and cirrhosis, and can be regarded as the hepatic manifestation of the metabolic syndrome (MetS). The initial stages of NAFLD are characterized by intra-hepatocyte l...

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Bibliographic Details
Main Authors: Larner, D, Morgan, S, Gathercole, L, Doig, C, Guest, P, Weston, C, Hazeldine, J, Tomlinson, J, Stewart, P, Lavery, G
Format: Journal article
Language:English
Published: Endocrine Society 2016