Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4^+ CD25 ^high T cells with susceptibility in Kenyans

Background: Immunity to malaria develops naturally in endemic regions, but the protective immune mechanisms are poorly understood. Many vaccination strategies aim to induce T cells against divers pre-erythrocytic antigens, but correlates of protection in the field have been limited. The objective of...

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Bibliographic Details
Main Authors: Todryk, S, Bejon, P, Mwangi, T, Plebanski, M, Urban, B, Marsh, K, Hill, A, Flanagan, K
Format: Journal article
Language:English
Published: Public Library of Science 2008
Subjects: