A comparison of clustering models for inference of T cell receptor antigen specificity

The vast potential sequence diversity of TCRs and their ligands has presented an historic barrier to computational prediction of TCR epitope specificity, a holy grail of quantitative immunology. One common approach is to cluster sequences together, on the assumption that similar receptors bind simil...

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Bibliografski detalji
Glavni autori: Hudson, D, Lubbock, A, Basham, M, Koohy, H
Format: Internet publication
Jezik:English
Izdano: 2023