High multiplicity HIV-1 cell-to-cell transmission from macrophages to CD4+ T cells limits antiretroviral efficacy

Few studies have examined the efficacy of antiretroviral therapy (ART) in the context of cell-to-cell transmission. We aimed to determine whether the activity of ART is limited by the mode of HIV-1 spread between cells and the type of immune cell implicated in transmission, or is independent of thes...

Full description

Bibliographic Details
Main Authors: Duncan, C, Russell, R, Sattentau, Q
Format: Journal article
Language:English
Published: Lippincott, Williams & Wilkins 2013