The p53 response: a new mitochondrial role for cofactor strap

The p53 response: a new mitochondrial role for cofactor strap

<p>Strap is a DNA damage responsive p53 cofactor, reflecting its control by the DNA damage signalling pathway. This study identified Strap at the mitochondria where it is damage regulated and can augment p53-dependent cytochrome c release leading to apoptosis. Moreover, p53 and Strap facilitat...

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Dettagli Bibliografici
Autore principale:	Maniam, S
Altri autori:	La Thangue, N
Natura:	Tesi
Lingua:	English
Pubblicazione:	2013
Soggetti:	Oncology

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