Increased global transcription activity as a mechanism of replication stress in cancer

Increased global transcription activity as a mechanism of replication stress in cancer

Cancer is a disease associated with genomic instability that often results from oncogene activation. This in turn leads to hyperproliferation and replication stress. However, the molecular mechanisms that underlie oncogene-induced replication stress are still poorly understood. Oncogenes such as HRA...

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Dettagli Bibliografici
Autori principali:	Kotsantis, P, Silva, L, Irmscher, S, Jones, R, Folkes, L, Gromak, N, Petermann, E
Natura:	Journal article
Lingua:	English
Pubblicazione:	Nature Publishing Group 2016

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