Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity.

Membrane microvesicle shedding is an active process and occurs in viable cells with no signs of apoptosis or necrosis. We report here that microvesicles shed by oligodendroglioma cells contain an 'aggrecanase' activity, cleaving aggrecan at sites previously identified as targets for adamal...

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Bibliographic Details
Main Authors: Lo Cicero, A, Majkowska, I, Nagase, H, Di Liegro, I, Troeberg, L
Format: Journal article
Language:English
Published: 2012