Immunofluorescence detection of clustered gamma-H2AX foci induced by HZE-particle radiation.

We studied the spatial and temporal distributions of foci of the phosphorylated form of the histone protein H2AX (gamma-H2AX), which is known to be activated by double-strand breaks after irradiation of human fibroblast cells with high-energy silicon (54 keV/microm) and iron (176 keV/microm) ions. H...

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Bibliographic Details
Main Authors: Desai, N, Davis, E, O'Neill, P, Durante, M, Cucinotta, F, Wu, H
Format: Journal article
Language:English
Published: 2005