Stereoselective spirolactam synthesis via palladium catalyzed arylative allene carbocyclization cascades.
A diastereoselective arylative carbocyclization of pro-nucleophile-linked allenes with aryl and heteroaryl halides to provide spirocyclic lactam products with moderate to high diastereoselectivities and good yields under Pd(0) catalysis is reported. Being operationally simple and tolerant of multipl...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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