KDM2B links recognition of CpG islands to polycomb domain formation in vivo

<p>Mammalian genomes are characterised by global and pervasive DNA methylation and this modification is generally thought to be inhibitory to transcription. An exception to this widespread DNA modification are genomic elements called CpG islands (CGI), contiguous regions of non-methylated DNA...

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Bibliographic Details
Main Author: Farcas, AM
Other Authors: Klose, RJ
Format: Thesis
Language:English
Published: 2013
Subjects: